Corpus ID: 19084451

Lipoxygenase inhibition and antioxidant properties of bisbenzylisoqunoline alkaloids isolated from Mahonia aquifolium.

@article{Bezkov1996LipoxygenaseIA,
  title={Lipoxygenase inhibition and antioxidant properties of bisbenzylisoqunoline alkaloids isolated from Mahonia aquifolium.},
  author={L. Bez{\'a}kov{\'a} and V. Mi{\vs}{\'i}k and L. M{\'a}lekov{\'a} and E. Svajdlenka and D. Kost{\'a}lov{\'a}},
  journal={Die Pharmazie},
  year={1996},
  volume={51 10},
  pages={
          758-61
        }
}
  • L. Bezáková, V. Mišík, +2 authors D. Kostálová
  • Published 1996
  • Chemistry, Medicine
  • Die Pharmazie
  • Products of lipoxygenase metabolism are known to play a role in the pathogenesis of psoriasis. Six bisbenzylisoquinoline (BBIQ) alkaloids, oxyacanthine, armoline, baluchistine, berbamine, obamegine, aquifoline, isolated from Mahonia aquifolium, were tested for lipoxygenase inhibition. Berbamine and oxyacanthine were the most potent lipoxygenase inhibitors, whereas aromoline and baluchistine exhibited only very low potencies. Oxyacanthine and berbamine were also among the most active compounds… CONTINUE READING
    27 Citations
    Mahonia Aquifolium Flowers Extract Effects in Acute Experimental Inflammation
    • 1
    • PDF
    The medicinal uses of the genus Mahonia in traditional Chinese medicine: An ethnopharmacological, phytochemical and pharmacological review.
    • 32
    • Highly Influenced
    Polar constituents of Ligustrum vulgare L. and their effect on lipoxygenase activity
    • 5
    Anti-Psoriasis Agents from Natural Plant Sources.
    • 11