Corpus ID: 19084451

Lipoxygenase inhibition and antioxidant properties of bisbenzylisoqunoline alkaloids isolated from Mahonia aquifolium.

@article{Bezkov1996LipoxygenaseIA,
  title={Lipoxygenase inhibition and antioxidant properties of bisbenzylisoqunoline alkaloids isolated from Mahonia aquifolium.},
  author={L. Bez{\'a}kov{\'a} and V. Mi{\vs}{\'i}k and L. M{\'a}lekov{\'a} and E. Svajdlenka and D. Kost{\'a}lov{\'a}},
  journal={Die Pharmazie},
  year={1996},
  volume={51 10},
  pages={
          758-61
        }
}

L. Bezáková, V. Mišík, +2 authors D. Kostálová

Published 1996

Chemistry, Medicine

Die Pharmazie

Products of lipoxygenase metabolism are known to play a role in the pathogenesis of psoriasis. Six bisbenzylisoquinoline (BBIQ) alkaloids, oxyacanthine, armoline, baluchistine, berbamine, obamegine, aquifoline, isolated from Mahonia aquifolium, were tested for lipoxygenase inhibition. Berbamine and oxyacanthine were the most potent lipoxygenase inhibitors, whereas aromoline and baluchistine exhibited only very low potencies. Oxyacanthine and berbamine were also among the most active compounds… CONTINUE READING

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