Lipoteichoic acid induces HO-1 expression via the TLR2/MyD88/c-Src/NADPH oxidase pathway and Nrf2 in human tracheal smooth muscle cells.

@article{Lee2008LipoteichoicAI,
  title={Lipoteichoic acid induces HO-1 expression via the TLR2/MyD88/c-Src/NADPH oxidase pathway and Nrf2 in human tracheal smooth muscle cells.},
  author={I-Ta Lee and S W Wang and Chiang-Wen Lee and Chia-Chi Chang and Chih-Chung Lin and S P Luo and Chuen-Mao Yang},
  journal={Journal of immunology},
  year={2008},
  volume={181 7},
  pages={5098-110}
}
Heme oxygenase (HO)-1 is a stress-inducible rate-limiting enzyme in heme degradation that confers cytoprotection against oxidative injury and provides a vital function in maintaining tissue homeostasis. Increasing reports have indicated that lipoteichoic acid (LTA) exerts as LPS as an immune system-stimulating agent and plays a role in the pathogenesis of… CONTINUE READING