Liposomes Coated with Isolated Macrophage Membrane Can Target Lung Metastasis of Breast Cancer.

@article{Cao2016LiposomesCW,
  title={Liposomes Coated with Isolated Macrophage Membrane Can Target Lung Metastasis of Breast Cancer.},
  author={Haiqiang Cao and Zhaoling Dan and Xinyu He and Zhiwen Zhang and Yaping Li and Qi Yin},
  journal={ACS nano},
  year={2016},
  volume={10 8},
  pages={
          7738-48
        }
}
Cancer metastasis leads to high mortality of breast cancer and is difficult to treat because of the poor delivery efficiency of drugs. Herein, we report the wrapping of a drug-carrying liposome with an isolated macrophage membrane to improve delivery to metastatic sites. The macrophage membrane decoration increased cellular uptake of the emtansine liposome in metastatic 4T1 breast cancer cells and had inhibitory effects on cell viability. In vivo, the macrophage membrane enabled the liposome to… CONTINUE READING
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