Liposome oxidation and erythrocyte lysis by enzymically generated superoxide and hydrogen peroxide.

@article{Kellogg1977LiposomeOA,
  title={Liposome oxidation and erythrocyte lysis by enzymically generated superoxide and hydrogen peroxide.},
  author={Ellen Kellogg and Irwin Fridovich},
  journal={The Journal of biological chemistry},
  year={1977},
  volume={252 19},
  pages={6721-8}
}
Xanthine oxidase, acting on acetaldehyde under aerobic conditions, produces a flux of O2- and H2O2 which attacks artificial liposomes and washed human erythrocytes. The liposomes were peroxidized and the erythrocytes suffered oxidation of hemoglobin followed by lysis. The oxidation of hemoglobin followed by lysis. The oxidation of hemoglobin, within the exposed erythrocytes, could be largely prevented by prior conversion to carbon monoxyhemoglobin, without preventing lysis. Hemolysis thus… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 72 extracted citations

Hemolysis of human red blood cells by riboflavin-Cu(II) system.

Biochimica et biophysica acta • 2000
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…