Liposome-induced activation of the classical complement pathway does not require immunoglobulin.

Abstract

We have investigated the contribution of immunoglobulin to the liposome-induced activation of complement in human serum. Liposomes containing the negatively charged phospholipids cardiolipin, phosphatidylglycerol or phosphatidylinositol, in addition to phosphatidylcholine and cholesterol, were used to activate complement in a whole serum system. The… (More)

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@article{Marjan1994LiposomeinducedAO, title={Liposome-induced activation of the classical complement pathway does not require immunoglobulin.}, author={Jahangiri Marjan and Z. Xie and Deirdre Devine}, journal={Biochimica et biophysica acta}, year={1994}, volume={1192 1}, pages={35-44} }