Liposome/DNA systems: correlation between association, hydrophobicity and cell viability

@article{Chiaramoni2007LiposomeDNASC,
  title={Liposome/DNA systems: correlation between association, hydrophobicity and cell viability},
  author={Nadia S Chiaramoni and Luc{\'i}a Speroni and Mar{\'i}a Cristina Taira and Silvia Del Valle Alonso},
  journal={Biotechnology Letters},
  year={2007},
  volume={29},
  pages={1637-1644}
}
Small unilamellar vesicles associated with plasmid DNA showed maximum association efficiency for a cationic mixture of egg phosphatidylcholine (EPC):1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE):di-1,2-dioleoyl-3-trimethyl ammonium propane (DOTAP) (16:8:1 molar ratio) [65%], followed by neutral lipids EPC:1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE):cholesterol (Chol) (2:2:1 molar ratio) [30%], and a polymerized formulation 1,2-bis(10,12-tricosadiynoyl)sn-glycero-3… CONTINUE READING