Liposome/DNA systems: correlation between hydrophobicity and DNA conformational changes.

@article{Chiaramoni2008LiposomeDNASC,
  title={Liposome/DNA systems: correlation between hydrophobicity and DNA conformational changes.},
  author={Nadia S Chiaramoni and Leticia Baccarini and Mar{\'i}a Cristina Taira and Silvia Del Valle Alonso},
  journal={Journal of biological physics},
  year={2008},
  volume={34 1-2},
  pages={179-88}
}
In a previous work, we found that liposome hydrophobicity could affect deoxyribonucleic acid (DNA) association efficiency. Now, we have focused on the possible correlation between liposome hydrophobicity and DNA conformation. DNA lyophilized with cationic vesicles with high hydrophobicity changes its conformation into a more condensed form, probably the C form. With noncharged vesicles, it changes its conformation from B to a partial A form. These results contribute to a better understanding of… CONTINUE READING