Liposomal mitoxantrone for the local treatment of peritoneal carcinomatosis induced by colon cancer cells in mice.

@article{Genne1994LiposomalMF,
  title={Liposomal mitoxantrone for the local treatment of peritoneal carcinomatosis induced by colon cancer cells in mice.},
  author={Ph Genne and Niels Olivier Olsson and Gabriel Guti{\'e}rrez and Olivier Duchamp and Bruno Chauffert},
  journal={Anti-cancer drug design},
  year={1994},
  volume={9 2},
  pages={73-84}
}
Since liposomes are slowly resorbed from serous cavities, they may constitute a valuable tool for the treatment of peritoneal carcinomatosis. We prepared mitoxantrone (MXN)-liposomes with various lipid compositions and checked their antitumoral activity on a peritoneal carcinomatosis induced by a colon cancer cell injection (1 x 10(5) C51 cells) in BALB/c… CONTINUE READING