Liposomal hydrogel formulation for transdermal delivery of pirfenidone.


CONTEXT Pirfenidone (PFD) is an anti-fibrotic and anti-inflammatory agent indicated for the treatment of idiopathic pulmonary fibrosis (IPF). The current oral administration of PFD has several limitations including first pass metabolism and gastrointestinal irritation. OBJECTIVE The aim of this study is to investigate the feasibility of transdermal… (More)
DOI: 10.3109/08982104.2015.1060611


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