Liposomal drug formulations. Rationale for development and what we can expect for the future.

@article{Allen1998LiposomalDF,
  title={Liposomal drug formulations. Rationale for development and what we can expect for the future.},
  author={Theresa M. Allen},
  journal={Drugs},
  year={1998},
  volume={56 5},
  pages={747-56}
}
Liposomes are versatile drug carriers which can be used to solve problems of drug solubility, instability and rapid degradation. Both hydrophilic and hydrophobic drugs can be associated with liposomes and special techniques have been developed for the efficient loading of weak acids and weak bases into liposomes. Liposomes can function as sustained release systems for drugs and the rate of release can be manipulated. Advantage can be taken of the substantial changes in pharmacokinetics which… CONTINUE READING