Liposomal amphotericin B: what is its role in 2008?

  title={Liposomal amphotericin B: what is its role in 2008?},
  author={Fanny Lanternier and Olivier Lortholary},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  volume={14 Suppl 4},
Although our antifungal armamentarium has been enlarged recently with new azoles (voriconazole and posaconazole) and echinocandins (caspofungin, micafungin, anidulafungin), the polyenes still have an important role in antifungal strategies because of their extended antifungal spectrum and rarity of mycological resistance. The use of conventional amphotericin B deoxycholate is limited by substantial toxicity that is either infusion-related or associated with renal failure. Its lipid derivatives… CONTINUE READING


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