Liposomal Systems as Nanocarriers for the Antiviral Agent Ivermectin.

@article{Croci2016LiposomalSA,
  title={Liposomal Systems as Nanocarriers for the Antiviral Agent Ivermectin.},
  author={Romina Croci and Elisabetta Bottaro and Kitti Wing Ki Chan and Satoru Watanabe and Margherita Pezzullo and Eloise Mastrangelo and Claudio Nastruzzi},
  journal={International journal of biomaterials},
  year={2016},
  volume={2016},
  pages={
          8043983
        }
}
RNA virus infections can lead to the onset of severe diseases such as fever with haemorrhage, multiorgan failure, and mortality. The emergence and reemergence of RNA viruses continue to pose a significant public health threat worldwide with particular attention to the increasing incidence of flaviviruses, among others Dengue, West Nile Virus, and Yellow Fever viruses. Development of new and potent antivirals is thus urgently needed. Ivermectin, an already known antihelminthic drug, has shown… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 23 REFERENCES

T

J.G.H. Low, E.-E. Ooi
  • Tolfvenstam et al., β€œEarly dengue infection and outcome study (EDEN)β€”study design and preliminary findings,” Annals of the Academy of Medicine Singapore, vol. 35, no. 11, pp. 783–789
  • 2006
VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL

J

E. Mastrangelo, S. Mazzitelli
  • Fabbri et al., β€œDelivery of suramin as an antiviral agent through liposomal systems,” ChemMedChem, vol. 9, no. 5, pp. 933–939
  • 2014
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

and S

S. Watanabe, K. W. Chan, G. Dow, E. E. Ooi, J. G. Low
  • G. Vasudevan, β€œOptimizing celgosivir therapy inmouse models of dengue virus infection of serotypes 1 and 2: the search for a window for potential therapeutic efficacy,” Antiviral Research, vol. 127, pp. 10–19
  • 2016
VIEW 1 EXCERPT

W

M.Y.F. Tay, J. E. Fraser
  • K. K. Chan et al., β€œNuclear localization of dengue virus (DENV) 1-4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin,” Antiviral Research, vol. 99, no. 3, pp. 301–306
  • 2013
VIEW 1 EXCERPT

and J

J. Rocha-Pereira, D. Jochmans, Y. Debing, E. Verbeken, M.S.J. Nascimento
  • Neyts, β€œThe viral polymerase inhibitor 2-cmethylcytidine inhibits norwalk virus replication and protects against norovirus-induced diarrhea and mortality in a mouse model,” Journal of Virology, vol. 87, no. 21, pp. 11798–11805
  • 2013
VIEW 1 EXCERPT

Iver - mectin is a potent inhibitor of flavivirus replication specifically targeting NS 3 helicase activity : new prospects for an old drug

M. Alvinerie, E. Escudero, J.-F. Sutra, C. Eeckhoutte, P. Galtier
  • Journal of Antimicrobial Chemotherapy
  • 2012

T

E. Mastrangelo, M. Pezzullo
  • De burghgraeve et al., β€œIvermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug,” Journal of Antimicrobial Chemotherapy, vol. 67, no. 8, pp. 1884– 1894
  • 2012