Liposomal Doxorubicin in the Treatment of Breast Cancer Patients: A Review

  title={Liposomal Doxorubicin in the Treatment of Breast Cancer Patients: A Review},
  author={Juan Lao and Julia Madani and Teresa Pu{\'e}rtolas and Mar{\'i}a Luz Alonso {\'A}lvarez and Alba Felix Moreno Hernandez and Roberto Antonio Pazo-Cid and {\'A}ngel Artal and Antonio Ant{\'o}n Torres},
  booktitle={Journal of drug delivery},
Drug delivery systems can provide enhanced efficacy and/or reduced toxicity for anticancer agents. Liposome drug delivery systems are able to modify the pharmacokinetics and biodistribution of cytostatic agents, increasing the concentration of the drug released to neoplastic tissue and reducing the exposure of normal tissue. Anthracyclines are a key drug in the treatment of both metastatic and early breast cancer, but one of their major limitations is cardiotoxicity. One of the strategies… CONTINUE READING
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