Lipoproteins inhibit macrophage activation by lipoteichoic acid.

  title={Lipoproteins inhibit macrophage activation by lipoteichoic acid.},
  author={Carl Grunfeld and Monique Marshall and Judy K. Shigenaga and Arthur H. Moser and Paris Tobias and Kennenth R Feingold},
  journal={Journal of lipid research},
  volume={40 2},
Regulation of lipid metabolism during infection is thought to be part of host defense, as lipoproteins neutralize endotoxin (LPS) and viruses. Gram-positive infections also induce disturbances in lipid metabolism. Therefore, we investigated whether lipoproteins could inhibit the toxic effects of lipoteichoic acid (LTA), a fragment of gram-positive bacteria. LTA activated RAW264.7 macrophage cells, stimulating production of tumor necrosis factor (TNF) in a dose-dependent matter, but produced… CONTINUE READING
51 Citations
75 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 51 extracted citations


Publications referenced by this paper.
Showing 1-10 of 75 references

Role of cytokines in acute phase response

  • C. Richards, J. Gauldie
  • Human Cytokines : Their Role in Disease and Ther
  • 1995
Highly Influential
6 Excerpts

port of the conference on low blood cholesterol : mortality associations

  • A. J. Claxton, D. R. Jacobs, C. Iribarren, S. L. Welles, S. Sidney, K. R. Feingold
  • 1998

Differential effects of reconstituted high-density lipoprotein on coagulation, fibrinolysis and platelet activation during human endotoxemia

  • D. Pajkrt, P. G. Lerch, +7 authors S. J. van Deventer
  • Thromb. Haemost
  • 1997

Similar Papers

Loading similar papers…