Lipoproteins and their receptors in embryonic development: more than cholesterol clearance.

  title={Lipoproteins and their receptors in embryonic development: more than cholesterol clearance.},
  author={Thomas E. Willnow and Annette Hammes and Suzanne Eaton},
  volume={134 18},
Previously, the relevance of lipoproteins and their receptors has mainly been discussed in terms of cholesterol clearance in the adult organism. Now, findings from nematodes to fruit flies to mammals all point towards novel and unexpected roles for lipoprotein metabolism in the control of key regulatory pathways in the developing embryo, including signaling through steroid hormones and throughout the hedgehog and Wnt signaling pathways. Here, we discuss the emerging view of how lipoproteins and… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
27 Extracted Citations
106 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 27 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 106 references

Familial hypercholesterolemia

  • J. L. Goldstein, H. H. Hobbs, M. S. Brown
  • The Metabolic and Molecular Basis of Inherited…
  • 2001
Highly Influential
3 Excerpts

Mutations in LRP 2 , which encodes the multiligand receptor megalin , cause DonnaiBarrow and faciooculoacousticorenal syndromes

  • S. Kantarci, L. Al-Gazali, +7 authors A. Teebi
  • Nat . Genet .
  • 2007
1 Excerpt

Similar Papers

Loading similar papers…