Lipoprotein-mediated transfer of 2,4,5,2',4',5'-hexachlorobiphenyl into cultured human cells.

@article{Shireman1988LipoproteinmediatedTO,
  title={Lipoprotein-mediated transfer of 2,4,5,2',4',5'-hexachlorobiphenyl into cultured human cells.},
  author={Rachel B. Shireman},
  journal={Xenobiotica; the fate of foreign compounds in biological systems},
  year={1988},
  volume={18 4},
  pages={449-57}
}
1. The very low density, low density and high density lipoproteins (VLDL, LDL, HDL), centrifugally separated from human plasma treated with 2,4,5,2',4',5'-hexachloro[14C]biphenyl (14C-HCB) contained approximately 50% of the 14C-HCB. 2. Normal skin fibroblasts were incubated at 4 degrees C for 37 degrees C for varying times with medium containing 10% serum, LDL or HDL labelled with 14C-HCB. Cellular incorporation of 14C-HCB from serum was temperature-dependent and occurred mainly during the… CONTINUE READING

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