Lipoprotein lipase mRNA expression in whole blood is a prognostic marker in B cell chronic lymphocytic leukemia.

@article{Bockstaele2007LipoproteinLM,
  title={Lipoprotein lipase mRNA expression in whole blood is a prognostic marker in B cell chronic lymphocytic leukemia.},
  author={Femke Van Bockstaele and Valerie Pede and Ann Janssens and Filip Callewaert and Fritz C. Offner and Bruno Verhasselt and Jan Philipp{\'e}},
  journal={Clinical chemistry},
  year={2007},
  volume={53 2},
  pages={204-12}
}
BACKGROUND Chronic lymphocytic leukemia (CLL) is characterized by high individual variability in clinical course and the need for therapy. Differentiation of prognostic subgroups is based primarily on the mutation status of the genes for the variable region of the immunoglobulin heavy chain (IGHV). The time- and labor-intensive nature of this analysis necessitates the use of easily applicable surrogate markers. METHODS We developed a quantitative PCR (qPCR) method for determining lipoprotein… CONTINUE READING

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