Lipoprotein lipase and endothelial lipase expression in mouse brain: regional distribution and selective induction following kainic acid-induced lesion and focal cerebral ischemia.

@article{Paradis2004LipoproteinLA,
  title={Lipoprotein lipase and endothelial lipase expression in mouse brain: regional distribution and selective induction following kainic acid-induced lesion and focal cerebral ischemia.},
  author={Eric Paradis and S{\'e}bastien Clavel and Pierre Julien and M. V. R. L. Murthy and Fabienne de Bilbao and Denis Arsenijevic and Panteleimon Giannakopoulos and Philippe G Vallet and Denis Richard},
  journal={Neurobiology of disease},
  year={2004},
  volume={15 2},
  pages={312-25}
}
Lipoprotein and endothelial lipases are members of the triglyceride lipase gene family. These genes are expressed in the brain, where the encoded proteins are fulfilling functions that have yet to be elucidated. In this study, we examined the distribution of their respective mRNAs in the C57BL/6 mouse brain by in situ hybridization. In control mice, we observed widespread expression of lipoprotein lipase (LPL) mRNA mainly in pyramidal cells of the hippocampus (CA1, CA2 and CA3 areas), in the… CONTINUE READING