Lipoprotein lipase: from gene to obesity.

  title={Lipoprotein lipase: from gene to obesity.},
  author={Hong X. Wang and Robert H Eckel},
  journal={American journal of physiology. Endocrinology and metabolism},
  volume={297 2},
Lipoprotein lipase (LPL) is a multifunctional enzyme produced by many tissues, including adipose tissue, cardiac and skeletal muscle, islets, and macrophages. LPL is the rate-limiting enzyme for the hydrolysis of the triglyceride (TG) core of circulating TG-rich lipoproteins, chylomicrons, and very low-density lipoproteins (VLDL). LPL-catalyzed reaction… CONTINUE READING