Lipoprotein glomerulopathy: significance of lipoprotein and ultrastructural features.

  title={Lipoprotein glomerulopathy: significance of lipoprotein and ultrastructural features.},
  author={Toshio Saito and Shinichi Oikawa and Hiroshi Sato and Takehiro Sato and Sadayoshi Ito and Jun Sasaki},
  journal={Kidney international. Supplement},
BACKGROUND Lipoprotein glomerulopathy (LPG) is a unique disease characterized by intraglomerular lipoprotein thrombi and type III hyperlipoproteinemia. Recently, we have demonstrated that LPG is associated with inherited apolipoprotein E (apoE) variants including apoE Sendai. On the other hand electron microscopy shows that intraglomerular lipoprotein thrombi consist of lipid granules of various sizes. To elucidate the relationship between the peculiar histology and abnormal lipid metabolism… CONTINUE READING


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