Lipoprotein-associated phospholipase A2 as a biomarker for coronary disease and stroke


Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet-activating factor acetylhydrolase, is a plasma enzyme that circulates bound to lipoproteins. The association between Lp-PLA2 and atherosclerosis is ambiguous, as it can both degrade and generate potentially damaging vasoactive molecules. In this article, we speculate that Lp-PLA2… (More)
DOI: 10.1038/ncpcardio0321


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