Lipoprotein-associated phospholipase A2, a novel cardiovascular inflammatory marker, in HIV-infected patients.

@article{Mangili2014LipoproteinassociatedPA,
  title={Lipoprotein-associated phospholipase A2, a novel cardiovascular inflammatory marker, in HIV-infected patients.},
  author={Alexandra Mangili and R T Nugraha Ahmad and Robert Lewis Wolfert and Jeffrey T. Kuvin and Joseph F. Polak and Richard H Karas and Christine A. Wanke},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2014},
  volume={58 6},
  pages={
          893-900
        }
}
BACKGROUND Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an emerging biomarker of cardiovascular disease. This study was conducted to describe the distribution of Lp-PLA2 in a cohort of human immunodeficiency virus (HIV)-infected adults and to determine associations between Lp-PLA2, cardiometabolic risk factors, and subclinical atherosclerosis in this population. METHODS Lp-PLA2 was assessed in 341 (25% women, 52% white, 74% on highly active antiretroviral therapy [HAART]) participants… CONTINUE READING
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