Lipoprotein (a) induces angiogenesis on the chick embryo chorioallantoic membrane.

  title={Lipoprotein (a) induces angiogenesis on the chick embryo chorioallantoic membrane.},
  author={Domenico Ribatti and Angelo Vacca and F Giacchetta and Simonetta Cesaretti and Mario Anichini and Luisa Roncali and F Damacco},
  journal={European journal of clinical investigation},
  volume={28 7},
BACKGROUND Both lipoprotein (a) [Lp(a)] and angiogenesis have been shown to be associated with initiation and progression of atherosclerotic plaque. Lp(a) and two neutralizing anti-Lp(a) antibodies were investigated for their capacity to affect the vasoproliferative processes of the chick embryo chorioallantoic membrane (CAM), a useful model for such an investigation. METHODS Gelatin sponges loaded with Lp(a) alone or together with anti-Lp(a) antibodies, or with vehicle alone, phosphate… CONTINUE READING

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