Lipoprotein(a) oxidation and autoantibodies: a new path in atherothrombosis.

  title={Lipoprotein(a) oxidation and autoantibodies: a new path in atherothrombosis.},
  author={Fredeswinda I Romero and Munther A. Khamashta and Graham R. V. Hughes},
  volume={9 3},
Lipoprotein(a) (Lp(a)) is considered a vascular pathogen of outstanding importance. High plasma levels of this lipoprotein are associated with premature arterial disease; however, the mechanisms involved have not been clarified. The atherosclerotic process is increasingly regarded as a chronic inflammatory reaction in the arterial wall where oxidation-mediated endothelial injury involving modified forms of low-density lipoprotein (LDL) seems to be a key event. Autoimmune pathways are involved… CONTINUE READING


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