Lipopolysaccharides from Helicobacter pylori can act as antagonists for Toll-like receptor 4.

@article{Lepper2005LipopolysaccharidesFH,
  title={Lipopolysaccharides from Helicobacter pylori can act as antagonists for Toll-like receptor 4.},
  author={Philipp Moritz Lepper and Martha Triantafilou and Christian Schumann and Elisabeth Marion Schneider and Kathy Triantafilou},
  journal={Cellular microbiology},
  year={2005},
  volume={7 4},
  pages={
          519-28
        }
}
Infection with Helicobacter pylori, a Gram-negative bacterium, is strongly associated with gastric ulcers and adenocarcinoma. The mechanisms by which the innate immune system recognizes H. pylori lipopolysaccharide (LPS) remain unclear. Contradictory reports exist that suggest that Toll-like receptors are involved. In this study we evaluated the interactions of Toll-like receptors with LPS from different strains of H. pylori. Using reporter cell lines, as well as HEK293 cells transfected with… CONTINUE READING

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