Lipopolysaccharide-pretreated plasmacytoid dendritic cells ameliorate experimental chronic kidney disease

@inproceedings{Zheng2012LipopolysaccharidepretreatedPD,
  title={Lipopolysaccharide-pretreated plasmacytoid dendritic cells ameliorate experimental chronic kidney disease},
  author={Dong Xia Zheng and Qi Cao and Vincent W. S. Lee and Ya na Wang and Guoping Zheng and Yuanmin Wang and Thian Kui Tan and Changqi Wang and Stephen I. Alexander and David C. H. Harris and Yiping Wang},
  booktitle={Kidney international},
  year={2012}
}
Plasmacytoid dendritic cells play important roles in inducing immune tolerance, preventing allograft rejection, and regulating immune responses in both autoimmune disease and graft-versus-host disease. In order to evaluate a possible protective effect of plasmacytoid dendritic cells against renal inflammation and injury, we purified these cells from mouse spleens and adoptively transferred lipopolysaccharide (LPS)-treated cells, modified ex vivo, into mice with adriamycin nephropathy. These LPS… CONTINUE READING

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