Lipopolysaccharide induces autotaxin expression in human monocytic THP-1 cells.


Autotaxin (ATX) is a secreted enzyme with lysophospholipase D (lysoPLD) activity, which converts lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA), a bioactive phospholipid involved in numerous biological activities, including cell proliferation, differentiation, and migration. In the present study, we found that bacterial lipopolysaccharide… (More)
DOI: 10.1016/j.bbrc.2008.11.047


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