Lipopolysaccharide-induced elaboration of interleukin 1 by human monocytes: use for detection of lipopolysaccharide in serum and the influence of serum-lipopolysaccharide interactions.

Abstract

An assay of interleukin 1 (IL-1) production by human monocytes was used to detect minute amounts of bacterial lipopolysaccharide (LPS) in sera or serum components designed for use in experiments or for injection into humans. Elaboration of IL-1 is a more sensitive criterion for the presence of LPS than is the rabbit pyrogenicity assay, and contamination of… (More)

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Cite this paper

@article{Northoff1987LipopolysaccharideinducedEO, title={Lipopolysaccharide-induced elaboration of interleukin 1 by human monocytes: use for detection of lipopolysaccharide in serum and the influence of serum-lipopolysaccharide interactions.}, author={Hinnak Northoff and Dan Gl{\"u}ck and A. Woelpl and Bernhard Kubanek and Christopher Galanos}, journal={Reviews of infectious diseases}, year={1987}, volume={9 Suppl 5}, pages={S599-601} }