Lipopolysaccharide-induced cyclooxygenase-2 expression in mouse transformed Clara cells.

  title={Lipopolysaccharide-induced cyclooxygenase-2 expression in mouse transformed Clara cells.},
  author={Rodney D. Britt and Morgan L Locy and Trent E. Tipple and L D Nelin and Lynette K. Rogers},
  journal={Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology},
  volume={29 1-2},
BACKGROUND/AIMS Exacerbation of innate immune responses can contribute to development of acute lung injury. Multiple cell populations, including the bronchiolar epithelium, coordinate these inflammatory responses. Clara cells, non-ciliated epithelial cells, are located in the distal airways in humans and conducting airways in mice. These cells actively participate in innate immune responses but their precise contributions remain poorly defined. METHODS To test the hypothesis that E. coli… CONTINUE READING