Lipopolysaccharide delays demyelination and promotes oligodendrocyte precursor proliferation in the central nervous system.

@article{Skripuletz2011LipopolysaccharideDD,
  title={Lipopolysaccharide delays demyelination and promotes oligodendrocyte precursor proliferation in the central nervous system.},
  author={Thomas Skripuletz and Elvira Miller and Lisa Grote and Viktoria Gudi and Refik Pul and Elke Verena Voss and Jelena Skuljec and Darius Moharregh-Khiabani and Corinna Trebst and Martin Stangel},
  journal={Brain, behavior, and immunity},
  year={2011},
  volume={25 8},
  pages={1592-606}
}
Systemic infection can influence the course in many diseases of the central nervous system (CNS) such as multiple sclerosis (MS), yet the relationship between infection outside the CNS and potential damage and/or protection within the CNS is still not understood. Activation of microglia is a characteristic feature of most CNS autoimmune disorders, including MS, and both protective and degenerative functions of microglia have been proposed. Hence, we analyzed the effects of a systemic… CONTINUE READING
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