Lipopolysaccharide binding proteins on polymorphonuclear leukocytes: comparison of adult and neonatal cells.

Abstract

We have previously shown that polymorphonuclear leukocytes (PMN) from cord blood of normal full-term infants have a decreased priming response to lipopolysaccharide (LPS) compared with PMN of adults. Because the reason for this difference is poorly understood, we compared LPS binding on PMN from adults and newborns by using a photoactivatable iodinated LPS… (More)

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