Lipopolysaccharide augments expression and secretion of vascular endothelial growth factor in rat ventricular myocytes.

Abstract

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor, is highly expressed in the myocardium under various stimuli including hypoxia and ischemia. On the other hand, lipopolysaccharide (LPS) causes systemic inflammatory response syndrome (SIRS), which consists of systemic pathophysiological changes related to vascular… (More)

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