Lipopolysaccharide and hypoxia significantly alters interleukin-8 and macrophage chemoattractant protein-1 production by human fibroblasts but not fibrosis related factors.

@article{Eleftheriadis2011LipopolysaccharideAH,
  title={Lipopolysaccharide and hypoxia significantly alters interleukin-8 and macrophage chemoattractant protein-1 production by human fibroblasts but not fibrosis related factors.},
  author={Th Eleftheriadis and Vassilios Liakopoulos and Benjamin J. Lawson and Georgia Antoniadi and Ioannis K. Stefanidis and Grammati Galaktidou},
  journal={Hippokratia},
  year={2011},
  volume={15 3},
  pages={
          238-43
        }
}
Besides extracellular matrix production, fibroblasts are able to produce various cytokines. Their ubiquitous position makes fibroblasts appropriate cells for sensing various noxious stimuli and for attracting immune cells in the affected area. In the present study the effect of lipopolysaccharide (LPS) and cobalt chloride (CoCl(2)) on the above fibroblasts functions were evaluated in primary human skin fibroblasts cultures. Collagen, matrix metalloproteinase-1, tissue inhibitor of… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 48 REFERENCES

Medical and endovascular management of critical limb ischemia.

  • Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
  • 2009

Fibrogenesis of parenchymal organs.

  • Proceedings of the American Thoracic Society
  • 2008