Lipopolysaccharide (LPS)-induced dopamine cell loss in culture: roles of tumor necrosis factor-alpha, interleukin-1beta, and nitric oxide.

@article{Gayle2002LipopolysaccharideD,
  title={Lipopolysaccharide (LPS)-induced dopamine cell loss in culture: roles of tumor necrosis factor-alpha, interleukin-1beta, and nitric oxide.},
  author={Dave A. Gayle and Zaodung Ling and ChongWai Tong and Teresa Landers and Jack W Lipton and Paul M. Carvey},
  journal={Brain research. Developmental brain research},
  year={2002},
  volume={133 1},
  pages={
          27-35
        }
}
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopamine (DA) neurons of the substantia nigra pars compacta (SNc). Although the exact mechanisms responsible for this cell loss are unclear, emerging evidence suggests the involvement of inflammatory events. In the present study, we characterized the effects of the proinflammatory bacteriotoxin lipopolysaccharide (LPS) on the number of tyrosine hydroxylase immunoreactive (THir) cells (used as an index for DA… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 55 CITATIONS

Physiology of RGS10 in Neurons and Immune Cells.

  • Progress in molecular biology and translational science
  • 2015

FILTER CITATIONS BY YEAR

2003
2018

CITATION STATISTICS

  • 1 Highly Influenced Citations

  • Averaged 2 Citations per year over the last 3 years

  • 33% Increase in citations per year in 2018 over 2017

Similar Papers

Loading similar papers…