Lipopolysaccharide (LPS)-binding proteins BPI and LBP form different types of complexes with LPS.

  title={Lipopolysaccharide (LPS)-binding proteins BPI and LBP form different types of complexes with LPS.},
  author={Peter S. Tobias and Katrin Soldau and Nicole M. Iovine and Peter Elsbach and Jeffrey R Weiss},
  journal={The Journal of biological chemistry},
  volume={272 30},
Lipopolysaccharide (LPS)-binding protein (LBP) and bactericidal/permeability-increasing protein (BPI) are closely related LPS-binding proteins whose binding to LPS has markedly different functional consequences. To gain better insight into the possible basis of these functional differences, the physical properties of LBP-LPS and BPI-LPS complexes have been compared in this study by sedimentation, light scattering, and fluorescence analyses. These studies reveal dramatic differences in the… CONTINUE READING

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