Lipopolysaccharide: an endotoxin or an exogenous hormone?

  title={Lipopolysaccharide: an endotoxin or an exogenous hormone?},
  author={John C. Marshall},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={41 Suppl 7},
Conventional models of the pathogenesis of sepsis assume that microorganisms or their products are necessarily injurious to the host. In contrast, an evolutionary perspective suggests that host-microbial interactions are a symbiotic model and that disease results from the disruption of a mutually beneficial homeostatic state. Lipopolysaccharide (LPS) from… CONTINUE READING