Corpus ID: 44755306

Lipophilicity of thiobarbiturates determined by TLC.

@article{Kepczyska2007LipophilicityOT,
  title={Lipophilicity of thiobarbiturates determined by TLC.},
  author={E. Kepczyńska and Ewa Obłoza and A. Stasiewicz-Urban and J. Bojarşki and A. Pyka},
  journal={Acta poloniae pharmaceutica},
  year={2007},
  volume={64 4},
  pages={
          295-302
        }
}
Lipophilicty of 29 thiobarbituric acid derivatives were assessed by reversed-phase thin-layer chromatography using methanol: water mixtures as a mobile phase. A linear relationship was found between RM values and methanol concentrations in the mobile phase. The retention parameter, RM0, was related to theoretical partition coefficients calculated by means of different theoretical procedures (AlogPs, IAlogP, miLogP, logPKowwin, xlogP). 
New Methodology for the Synthesis of Thiobarbiturates Mediated by Manganese(III) Acetate

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