Lipophilic antioxidant U-18 and superoxide dismutase prevent cultured hippocampal neurons from destruction during hypoxia and in the posthypoxic period

The lipophilic antioxidant U-18 from the class of hindered phenols prevents the destruction of cultured hippocampal neurons during hypoxia and also in the posthypoxic reoxygenation period, apparently by being stably incorporated into their phospholipid membranes and by safeguarding these from free-radical damage in the course of reoxygenation. On the other… CONTINUE READING