Lipopeptides from Bacillus and Paenibacillus spp.: A Gold Mine of Antibiotic Candidates

@article{Cochrane2016LipopeptidesFB,
  title={Lipopeptides from Bacillus and Paenibacillus spp.: A Gold Mine of Antibiotic Candidates},
  author={S. Cochrane and J. Vederas},
  journal={Medicinal Research Reviews},
  year={2016},
  volume={36}
}
The emergence of multidrug‐resistant bacteria has placed a strain on health care systems and highlighted the need for new classes of antibiotics. Bacterial lipopeptides are secondary metabolites, generally produced by nonribosomal peptide synthetases that often exhibit broad‐spectrum antimicrobial activity. Only two new structural types of antibiotics have entered the market in the last 40 years, linezolid and the bacterial lipopeptide daptomycin. A wide variety of bacteria produce lipopeptides… Expand
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References

SHOWING 1-10 OF 178 REFERENCES
EM49: A NEW POLYPEPTIDE ANTIBIOTIC ACTIVE AGAINST CELL MEMBRANES
...
1
2
3
4
5
...