Lipogenesis in myoblasts and its regulation of CTRP6 by AdipoR1/Erk/PPARγ signaling pathway.

@article{Wu2016LipogenesisIM,
  title={Lipogenesis in myoblasts and its regulation of CTRP6 by AdipoR1/Erk/PPARγ signaling pathway.},
  author={Wenjing Wu and Yunmei Sun and Chen Zhao and Cunzhen Zhao and Xiaochang Chen and Guoqiang Wang and Wei-jun Pang and Gong She Yang},
  journal={Acta biochimica et biophysica Sinica},
  year={2016},
  volume={48 6},
  pages={509-19}
}
The induced lipogenesis and its regulation in C2C12 myoblasts remain largely unclear. Here, we found that the cocktail method could significantly induce lipogenesis through regulating lipid metabolic genes and Erk1/2 phosphorylation in myoblasts. Meanwhile, the expression and secretion of CTRP6 were increased during ectopic lipogenesis. Moreover, CTRP6… CONTINUE READING