Lipofuscin of the retinal pigment epithelium: A review

@article{Kennedy1995LipofuscinOT,
  title={Lipofuscin of the retinal pigment epithelium: A review},
  author={Chris J Kennedy and Piroska Elizabeth Rakoczy and Ian Jeffrey Constable},
  journal={Eye},
  year={1995},
  volume={9},
  pages={763-771}
}
Accumulation of lipofuscin is one of the most characteristic features of ageing observed in retinal pigment epithelial (RPE) cells. The lipofuscin found in RPE cells differs from that of other body tissues due to the fact that it is mainly derived from the chemically modified residues of incompletely digested photoreceptor outer segments. It is a heterogeneous material composed of a mixture of lipids, proteins, and different fluorescent compounds, the main fluorophore of which has recently been… CONTINUE READING

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