Lipofuscin in the cerebellar cortex of albino rats: An electron microscopic study

  title={Lipofuscin in the cerebellar cortex of albino rats: An electron microscopic study},
  author={Helmut Heinsen},
  journal={Anatomy and Embryology},
The ultrastructure of autofluorescent, PAS-positive lipofuscin in Purkinje, granule, Golgi epithelial, basket and stellate, microglial and perivascular cells in the cerebellar cortex of senescent rats is described. The membrane-bounded pigment is composed of three elements: 1) electron-lucent homogeneous droplets, 2) a granular matrix and 3) intensely osmiophilic patches. The proportions of these three components vary between cell types and one can grossly differentiate a neuronal and a glial… CONTINUE READING

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