Lipofuscin in neuronal aging and diseases.

  title={Lipofuscin in neuronal aging and diseases.},
  author={Paul Glees and M. D. Siam Hasan},
  journal={Normale und pathologische Anatomie},
The increasing intraneuronal accumulation of lipofuscin has been linked to the aging process by a striking linear correlation between the degree of accumulation and chronological age. It has been established that age pigments are soluble in polar and nonpolar solvents; the pigment is autofluorescent and stains with PAS, Sudan black B, Nile blue osmic acid and ferric ferricyanide techniques. Whether all pigments exhibiting these properties are identical, or at least closely related, regardless… CONTINUE READING
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