Lipodystrophy: pathophysiology and advances in treatment

  title={Lipodystrophy: pathophysiology and advances in treatment},
  author={Christina G. Fiorenza and Sharon Chou and Christos Socrates Mantzoros},
  journal={Nature Reviews Endocrinology},
Lipodystrophy is a medical condition characterized by complete or partial loss of adipose tissue. Not infrequently, lipodystrophy occurs in combination with pathological accumulation of adipose tissue at distinct anatomical sites. Patients with lipodystrophy exhibit numerous metabolic complications, which indicate the importance of adipose tissue as an active endocrine organ. Not only the total amount but also the appropriate distribution of adipose tissue depots contribute to the metabolic… CONTINUE READING


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