Lipodystrophy: pathophysiology and advances in treatment

@article{Fiorenza2011LipodystrophyPA,
  title={Lipodystrophy: pathophysiology and advances in treatment},
  author={Christina G. Fiorenza and Sharon Chou and Christos Socrates Mantzoros},
  journal={Nature Reviews Endocrinology},
  year={2011},
  volume={7},
  pages={137-150}
}
Lipodystrophy is a medical condition characterized by complete or partial loss of adipose tissue. Not infrequently, lipodystrophy occurs in combination with pathological accumulation of adipose tissue at distinct anatomical sites. Patients with lipodystrophy exhibit numerous metabolic complications, which indicate the importance of adipose tissue as an active endocrine organ. Not only the total amount but also the appropriate distribution of adipose tissue depots contribute to the metabolic… CONTINUE READING

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References

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Showing 1-10 of 248 references

HIV infection, HAART, and endothelial adhesion molecules: current reviewS nrendo_199_MAR11.indd

  • K. de Gaetano Donati, R. Rabagliati, L. Iacoviello, R. Cauda
  • perspectives. Lancet Infect. Dis
  • 2011

Leptin hormonal kinetics in the reviewS nrendo_199_MAR11.indd

  • S. L. wong, A. M. DePaoli, J. H. Lee, C. S. Mantzoros
  • J. Clin. Endocrinol. Metab
  • 2011

A 48-week randomized study of uridine supplementation vs switch to TDF on limb fat, mitochondrial function, inflammation, and bone mineral density in HIV lipoatrophy

  • McComsey, A G.
  • 17th Conference on Retroviruses and Opportunistic…
  • 2010

A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophy

  • Raboud, M J.
  • HIV Clin. Trials 11,
  • 2010

Effects of tesamorelin , a growth hormone - releasing factor , in HIV - infected patients with abdominal fat accumulation : a randomized placebo - controlled trial with a safety extension

  • J. Falutz
  • J . Aquir . Immune Defic . Syndr .
  • 2010

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