• DOI:10.1016/0026-0495(88)90151-5
Corpus ID: 19653357

Lipodystrophic diabetes mellitus. Investigations of lipoprotein metabolism and the effects of omega-3 fatty acid administration in two patients.

@article{Stacpoole1988LipodystrophicDM,
  title={Lipodystrophic diabetes mellitus. Investigations of lipoprotein metabolism and the effects of omega-3 fatty acid administration in two patients.},
  author={P. Stacpoole and J. Alig and L. Kilgore and C. Ayala and P. Herbert and L. Zech and W. R. Fisher},
  journal={Metabolism: clinical and experimental},
  year={1988},
  volume={37 10},
  pages={
          944-51
        }
}

P. Stacpoole, J. Alig, +4 authors W. R. Fisher

Published 1988

Biology, Medicine

Metabolism: clinical and experimental

We investigated the metabolic effects of omega-6 (safflower oil) and omega-3 (fish oil) fatty acid-enriched diets (65% carbohydrate, 20% fat) in two patients with a syndrome of diabetes mellitus, lipodystrophy, acanthosis nigricans, chylomicronemia, and abdominal pain. 3H-glycerol was used to evaluate triglyceride-rich lipoprotein-triglyceride (TRLP-TG) metabolism, and changes in glucose and insulin dynamics were also studied. On the omega-6 diet, both subjects demonstrated four- to five-times… CONTINUE READING

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