Lipocalins as a scaffold.

  title={Lipocalins as a scaffold.},
  author={Arne Skerra},
  journal={Biochimica et biophysica acta},
  volume={1482 1-2},
  • Arne Skerra
  • Published 2000 in Biochimica et biophysica acta
The concept of scaffolds that can be equipped with artificial biochemically active sites has gained recent interest in the field of protein design. Members of the lipocalin protein family represent promising model systems in this respect. Especially prototypic lipocalins, such as the retinol-binding protein or the bilin-binding protein (BBP), exhibit a structurally simple one-domain fold with a conformationally well conserved beta-barrel as their central motif. This type of supersecondary… CONTINUE READING


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