Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death.


L-PGDS [lipocalin-type PGD (prostaglandin D) synthase] is a dual-functional protein, acting as a PGD2-producing enzyme and a lipid transporter. L-PGDS is a member of the lipocalin superfamily and can bind a wide variety of lipophilic molecules. In the present study we demonstrate the protective effect of L-PGDS on H2O2-induced apoptosis in neuroblastoma… (More)
DOI: 10.1042/BJ20111889


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