Lipocalin-2 is associated with radioresistance in oral cancer and lung cancer cells.

@article{Shiiba2013Lipocalin2IA,
  title={Lipocalin-2 is associated with radioresistance in oral cancer and lung cancer cells.},
  author={Masashi Shiiba and Kengo Saito and Kazuaki Fushimi and Takashi Ishigami and Keiji Shinozuka and Dai Nakashima and Yukinao Kouzu and Hirofumi Koike and Atsushi Kasamatsu and Yosuke Sakamoto and Katsunori Ogawara and Katsuhiro Uzawa and Yuichi Takiguchi and Hideki Tanzawa},
  journal={International journal of oncology},
  year={2013},
  volume={42 4},
  pages={1197-204}
}
The aim of the present study was to identify a target molecule that could predict the efficacy of radiotherapy in oral squamous cell carcinoma (OSCC). We used DNA microarray analysis to identify differences in gene expression after X-ray irradiation. We compared the gene expression profiles between X-ray (8 Gy)-irradiated Ca9-22 cells (an OSCC-derived cell line) and unirradiated Ca9-22 cells. A total of 167 genes with a 2-fold higher level of expression induced by X-ray irradiation were… CONTINUE READING

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