Lipocalin-2: a New Regulator of Non-Pathogen- Associated Neuroinflammation

  title={Lipocalin-2: a New Regulator of Non-Pathogen- Associated Neuroinflammation},
  author={M. Banjara},
  journal={Clinical and experimental neurology},
  • M. Banjara
  • Published 2014
  • Biology
  • Clinical and experimental neurology
Lipocalin is a family of small molecules transporting extracellular proteins. Lipocalin-2 (LCN2) is a member of the family that sequesters iron-bound bacterial siderophores. The well-accepted function of LCN2 protein is its anti-bacterial behavior, however, its role in iron regulation, cellular migration, death and morphology modulation have been speculated. Several reports have correlated the presence of LCN2 in the infected, injured and stressed brain, and its effect in neuronal and non… Expand
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