Lipins: multifunctional lipid metabolism proteins.

@article{Csaki2010LipinsML,
  title={Lipins: multifunctional lipid metabolism proteins.},
  author={Lauren S Csaki and Karen Reue},
  journal={Annual review of nutrition},
  year={2010},
  volume={30},
  pages={257-72}
}
The lipin proteins are evolutionarily conserved proteins with roles in lipid metabolism and disease. There are three lipin protein family members in mammals and one or two orthologs in plants, invertebrates, and single-celled eukaryotes. Studies in yeast and mouse led to the identification of two distinct molecular functions of lipin proteins. Lipin proteins have phosphatidate phosphatase activity and catalyze the formation of diacylglycerol in the glycerol-3-phosphate pathway, implicating them… CONTINUE READING
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